Keys: Brian Eno, Ray Manzerak

Bass: John Entwistle

Guitar: Jimmy Page

Drums: Keith Moon

I think buckethead is one of the greatest all around instrumentalists of today. The Band is the greatest band of instrumentalists ever

Guitar:

• Preston Reed
• John Petrucci
• Jeff Loomis

Bass:

• Les Claypool
• Flea
• Aram Bedrosian
• John Myung

I really suggest you check out Aram Bedrosian and Preston Reed if you havent before. I would post some links but i can't yet because i am new here

I'm not totally sure whether you meant just guitars and drums but my definition of an instrumentalist would also expand to trumpet players and other instruments so mine must be Doc Severinson :)

drum : Mike Mangini

Igooooooor Presnyakov! I think that's how it's spelled.

Guitar is easy
 

Guitar: Yngwie Malmsteen easily

Bass: Jan-Olof Strandberg

Guitar: Johnny Smith