Y'all ever heard of self-trepanation? It's where you drill a hole in your head, effectively causing a permanent trip.
Bart Hughes developed the idea in Homo Sapiens Correctus, basing it off of treatments found in ancient skulls believed to relieve pressure from the brain. His thought is that the human body hasn't fully adapted to the shift to bipedalism and doesn't provide enough spinal fluid to the brain, limiting its faculties. He also believes that babies being born with a hole in the head to relieve pressure is the source of the almost psychedelic nature of childhood. By drilling a hole in his head, he changed the ratio of blood to spinal fluid in his head, increasing the level of oxygen going to his brain and putting it into an overactive state akin to a DMT trip. Some advocates have done it and say there is no going back.
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Originally Posted by Joe Mellen
It's really obvious when you get all the way through the skull. Quite a lot of blood comes out, and the drill bit goes in by an inch.
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The Homo Sapiens Correctus scroll:
Photos of people during and after trepanation, spoilered for blood.
Sounds like a good time with the homies