Quote:
Originally Posted by oojay
I think that taking it on a mostly empty stomach is really the trick about the vitamin C potentiation. If the vitamin C is basically the only thing in your system, it can potentiate the absorption of the shrooms you are taking. The ascorbic acid in most vitamin C sources helps to prevent the degredation of psilocin (which is what your body breaks psilocybin down in to). Also, ascorbic acid is capable of crossing the blood-brain barrier, meaning that any drugs in your system are more like to cross it as well, thus enhancing your trip.
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Most of that makes sense, but taking anything on an empty stomach is going to have a potentiative effect in comparison to the opposite.
As far as the effect of vitamin C in relation to your perceived experience, I think it would be too negligible to be remarked on. I know anecdotal evidence can't prove anything, and that's especially the case with this kind of thing, but (on a mostly empty stomach, as always) I've pre-loaded high doses of C, and in other scenarios, dosed during the trip, and I've never noticed any difference other than the variable nature of the trips themselves... as it's very hard, if not impossible without scientific testing, to determine exactly how much of the psychoactive you're actually ingesting. Not to mention all the other variables that come into play regarding the state of your body at the time of ingestion.
All I'm saying is even if it can be tested and proven that C potentiates a trip, I don't think a person could objectively differentiate between its effects and the variable nature of the drug itself. So ultimately, I wouldn't go out of my way to integrate C into a trip unless I was given to placebo effect.